People with obesity more risk of colon cancer

A research team led by a group of the area of Intestinal immunomodulation of the Granada Biosanitary Research Institute has published a scientific review “that could change our understanding about the link between the Obesity and colorectal cancer“, also known as Colon cancerwhich indicates that the Intestinal microbiota is clue In this relationship.

This has been announced in a statement, in which they have indicated that this study has been done in collaboration with the group of Hepatogastroenterology, pharmacology and clinical translational therapeutics of Ibima Bionand platform.

The study is titled Systematic Review: The Gut Microbiota As a Link Between Colorectal Cancer and Obesity And it has been published in the magazine Obesity Reviews. It analyzes more than one hundred studies that explore how Alterations in the intestinal flora They can explain why people with obesity They present a greater risk of developing Colon cancer.

“Our work shows that intestinal bacteria are not mere spectators, but active agents in it Tumor development. Specifically, the Intestinal dysbiosisan alteration in the microbial balance, could act as a bridge between two of the main epidemics of the 21st century: Obesity and colorectal cancer, “explained the principal investigator of the aforementioned study, the doctor Antonio Jesús Ruiz-Malagón.

Ruiz-Malagón and the doctor María Jesús Rodríguez-Sojo They have led this research as main co -authors and have also had the participation of scientists Eduardo Redondo, María Elena Rodríguez-Cabezas, Julio Gálvez and Alba Rodríguez-Nogalesreferents in the Microbioma study and its impact on health.

Ruiz-Malagón has added that “detect Microbiota changes could become a D toolEarly iagnosis. In addition, this opens the door to Personalized treatments based on Probioticsdiet or even fecal microbiota transplants. “

Raúl J. AndradeVice -Director Scientist of Ibima Bionand platform and responsible for the aforementioned research group, adds that “this work is an example of how translational research can help us understand Complex and multifactorial diseases like him cancer“. In this line, Andrade has added that” also puts on the table the need for address obesity Not only as a Metabolic problembut also as a Oncological Risk Factor“

This finding comes in a key momentthey have pointed out, since colorectal cancer is the Second deadly in the world and its incidence Keep increasing. According to recent data, more than 1.9 million new cases to global level And obesity is one of the main modifiable factors associated with its development, as detailed by the aforementioned statement.