Anacardo plant, allied against cell aging

The leaves and the cortex of the Anacardo plant have a high antioxidant potential for the development of treatments against cell aging and age -related disorders.

This is the main result of the study led by the doctor Eloy Bejarano FernándezRamón y Cajal researcher at the CEU Cardenal Herrera University (CEU UCH), where he leads the Research group in cell aging and nutrition.

His work, published in the International Scientific Magazine Antioxidantshas been carried out in collaboration with researchers from the United States, Canada and Guadalupe, and reveals which aerial parties of The Anacardo Plant They are more suitable for obtaining antioxidant extracts.

In his research, the teacher led by the teacher Bejaranoof the CEU UCH, has performed a phytochemical, electrochemical and biological characterization of the antioxidant potential of aqueous extracts of the air parts of the anacardo (Anacardium Westernly): the leaves, the cortex, the fruit and the nut of the anacardo, which They are traditionally used in popular medicine.

These extracts have been analyzed through different spectroscopy techniques, of polyphenols quantification and through antioxidant capacity tests. The biological activity of extracts from the Anacardo plant It has been evaluated in different mouse and human lines.

Therapeutic potential

According to Professor Bejarano“Our findings highlight the high therapeutic potential of leaves of leaves and cortex of the anacardo plant as very effective natural antioxidants”.

In contrast, fruit and nut extracts showed a minimal antioxidant activity and did not cause a significant modulation of genes that protect us from oxidative stress. For this reason we think Plant leaves and bark are better candidates to design phytotherapeutic treatments To combat cell aging, an area in which we are already working from our laboratory at the CEU UCH “.

In addition to the publication in AntioxidantsProfessor Bejarano has also presented these results as a guest speaker at two congresses: the Cellular Aging and Metabolism Symposium 2025 (CAMS2025)held at the University of A Coruña, and in the last Congress of the Spanish Society of Geriatrics and Gerontology (SEGG2025)held in Barcelona.

In this study, group in the group in cell aging and nutrition at the CEU UCH Eloy Bejarano, Alejandro Ponce, Lucía Gimeno, Alicia Doménech and Antonella Locascio They have collaborated with the professor of the Department of Biomedical Sciences of the CEU UCH Salvatore Sauro and with researchers from the Institute of Molecular Medicine applied at the CEU San Pablo University of Madrid; the Department of Pharmacology of The State University of New Jersey, in the United States; The Metabolomics Innovation Center (TMIC) and the Department of Chemistry of the University of Alberta, in Canada and the Covachim-M2E laboratory of the University of Las Antillas, on the French island of Guadalupe.